Metabolically Independent and Accurately Adjustable Aspergillus sp. Expression System

Metabolically independent and accurately adjustable Aspergillus sp. expression system.

Filamentous fungi are well-established expression hosts often used to produce extracellular proteins of use in the food and pharmaceutical industries. The expression systems presently used in Aspergillus species rely on either strong constitutive promoters, e.g., that for glyceraldehyde-3-phosphate dehydrogenase, or inducible systems derived from metabolic pathways, e.g., glaA (glucoamylase) or...

Fungal gene expression on demand: an inducible, tunable, and metabolism-independent expression system for Aspergillus niger.

Filamentous fungi are the cause of serious human and plant diseases but are also exploited in biotechnology as production platforms. Comparative genomics has documented their genetic diversity, and functional genomics and systems biology approaches are under way to understand the functions and interaction of fungal genes and proteins. In these approaches, gene functions are usually inferred fro...

An Antiphage Agent Isolated from Aspergillus Sp.

Aspergillus bertholletius sp. nov. from Brazil Nuts

During a study on the mycobiota of brazil nuts (Bertholletia excelsa) in Brazil, a new Aspergillus species, A. bertholletius, was found, and is described here. A polyphasic approach was applied using morphological characters, extrolite data as well as partial β-tubulin, calmodulin and ITS sequences to characterize this taxon. A. bertholletius is represented by nineteen isolates from samples of ...

Solving Polynomial System Efficiently and Accurately

We consider the problem of finding the isolated common roots of a set of polynomial functions defining a zero-dimensional ideal I in a ring R of polynomials over C. Normal form algorithms provide an algebraic approach to solve this problem. We use new characterizations of normal forms and describe accurate and efficient constructions that allow us to compute the algebra structure of R/I, and he...